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It did not, nonetheless, embrace sometimes substantial manufacturer rebates, and the drug makers' commerce group warned that omission distorted the precise cost.
Carboplatin combination remedy has been the mainstay of administration of platinum-sensitive recurrent cancers 2 The shift of focus to targeted therapies unearthed a number of candidates with promising scientific outcomes three , four ; nonetheless, effective new drugs in relapsing ovarian cancer remain an unmet medical want.
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To calculate the prices that are related to a typical 1-yr payer time horizon, the model assumes that after completing a course of therapy on the median duration of therapy, sufferers stay with out illness progression till reaching the median PFS that was reported within the pivotal medical trial for every drug or treatment routine.